Malignant gastrointestinal stromal tumor originating in the lesser omentum, complicated by rapidly progressive glomerulonephritis and gastric carcinoma.
نویسندگان
چکیده
A 69-year-old man was admitted with a large elastic mass in the upper abdomen. Computed tomography revealed a massive tumor in contact with the liver and gastrointestinal endoscopy revealed a gastric adenocarcinoma. He developed acute renal failure with massive proteinuria and died with a marked enlargement of the tumor. Autopsy revealed a tumor located in the lesser omentum. The tumor was considered to be a Gastrointestinal Stromal Tumor (GIST) because it was positive for c-kit. In addition, crescent formations and immune complexes in glomeruli were observed. We report the first case of GIST complicated by rapidly progressive glomerulonephritis and gastric carcinoma.
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small meals (owing to distortion of the stomach and cardio-oesophageal junction); and (5) an abdominal fluid thrill but no shifting dullness, indicating a localised collection of fluid and clotted blood. The likely pathogenesis of the haemorrhage is over-distension of the stomach with tearing of a small blood vessel in the lesser omentum. The blood tracks inferiorly, stripping peritoneum from t...
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عنوان ژورنال:
- Internal medicine
دوره 43 2 شماره
صفحات -
تاریخ انتشار 2004